Paul Guilhamon

Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy

Xiaoyang Lan, David J. Jörg, Florence M.G. Cavalli et al. · Nature · 2017 · 408 citations · Full text

Neuro-oncology, Embryonic Stem Cell, Lineage Plasticity +11

Gradient of Developmental and Injury Response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneity

Laura M. Richards, Owen Whitley, Graham MacLeod et al. · Nature Cancer · 2021 · 306 citations

Neuro-oncology, Transcriptional Regulation, Lineage Plasticity +10

Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas

Brian Krug, Nicolas Jay, Ashot S. Harutyunyan et al. · Cancer Cell · 2019 · 252 citations · Full text

Neuro-oncology, Glioma, Medicine +10

Integrated (epi)-Genomic Analyses Identify Subgroup-Specific Therapeutic Targets in CNS Rhabdoid Tumors

Jonathon Torchia, Brian Golbourn, Shengrui Feng et al. · Cancer Cell · 2016 · 251 citations · Full text

Tumor Biology, Radiation Oncology, Neuro-oncology +11

ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells

Nicole I. Park, Paul Guilhamon, Kinjal Desai et al. · Cell stem cell · 2017 · 215 citations

Chromatin, Neuro-oncology, Glioblastoma Stem Cells +13