Heike Niessner

T-helper-1-cell cytokines drive cancer into senescence

Heidi Braumüller, Thomas Wieder, Ellen Brenner et al. · Nature · 2013 · 705 citations

Cancer Immunosurveillance, Cellular Senescence, Medicine +3

Targeting hyperactivation of the <scp>AKT</scp> survival pathway to overcome therapy resistance of melanoma brain metastases

Heike Niessner, Andrea Forschner, Bernhard Klumpp et al. · Cancer Medicine · 2012 · 151 citations · Full text

Vemurafenib Potently Induces Endoplasmic Reticulum Stress–Mediated Apoptosis in BRAFV600E Melanoma Cells

Daniela Beck, Heike Niessner, Keiran S.M. Smalley et al. · Science Signaling · 2013 · 141 citations · Full text

Inhibition of PI3K-AKT-mTOR Signaling Sensitizes Melanoma Cells to Cisplatin and Temozolomide

Tobias Sinnberg, Konstantinos Lasithiotakis, Heike Niessner et al. · Journal of Investigative Dermatology · 2008 · 137 citations · Full text

Cell Regulation, Medicine, Receptor Tyrosine Kinase +6

Cancer immune control needs senescence induction by interferon-dependent cell cycle regulator pathways in tumours

Ellen Brenner, Barbara F. Schörg, Fatima Ahmetlić et al. · Nature Communications · 2020 · 130 citations · Full text