Tobias Sinnberg

Tumor mutation burden and circulating tumor DNA in combined CTLA-4 and PD-1 antibody therapy in metastatic melanoma – results of a prospective biomarker study

Andrea Forschner, Florian Battke, Dirk Hadaschik et al. · Journal for ImmunoTherapy of Cancer · 2019 · 211 citations · Full text

Medicine, Immunology, Oncology +17

Targeting hyperactivation of the <scp>AKT</scp> survival pathway to overcome therapy resistance of melanoma brain metastases

Heike Niessner, Andrea Forschner, Bernhard Klumpp et al. · Cancer Medicine · 2012 · 152 citations · Full text

Medicine, Oncology, Pharmacology +17

Combined Inhibition of MAPK and mTOR Signaling Inhibits Growth, Induces Cell Death, and Abrogates Invasive Growth of Melanoma Cells

Konstantinos Lasithiotakis, Tobias Sinnberg, Birgit Schittek et al. · Journal of Investigative Dermatology · 2008 · 148 citations

Life Sciences, Cell Biology, Oncology +17

Vemurafenib Potently Induces Endoplasmic Reticulum Stress–Mediated Apoptosis in BRAFV600E Melanoma Cells

Daniela Beck, Heike Niessner, Keiran S.M. Smalley et al. · Science Signaling · 2013 · 144 citations · Full text

Life Sciences, Oncology, Pharmacology +12

miR-137 Inhibits the Invasion of Melanoma Cells through Downregulation of Multiple Oncogenic Target Genes

Chonglin Luo, Paul W. Tetteh, P. Merz et al. · Journal of Investigative Dermatology · 2012 · 139 citations · Full text

Medicine, Molecular Biology, Oncology +14