Daniela Beck

Targeting hyperactivation of the <scp>AKT</scp> survival pathway to overcome therapy resistance of melanoma brain metastases

Heike Niessner, Andrea Forschner, Bernhard Klumpp et al. · Cancer Medicine · 2012 · 151 citations · Full text

Vemurafenib Potently Induces Endoplasmic Reticulum Stress–Mediated Apoptosis in BRAFV600E Melanoma Cells

Daniela Beck, Heike Niessner, Keiran S.M. Smalley et al. · Science Signaling · 2013 · 141 citations · Full text

The Farnesyl Transferase Inhibitor Lonafarnib Inhibits mTOR Signaling and Enforces Sorafenib-Induced Apoptosis in Melanoma Cells

Heike Niessner, Daniela Beck, Tobias Sinnberg et al. · Journal of Investigative Dermatology · 2010 · 66 citations · Full text

Tumor Biology, Medicine, Enforces Sorafenib-induced Apoptosis +9

BRAF Inhibitors Amplify the Proapoptotic Activity of MEK Inhibitors by Inducing ER Stress in NRAS-Mutant Melanoma

Heike Niessner, Tobias Sinnberg, Corinna Kosnopfel et al. · Clinical Cancer Research · 2017 · 47 citations · Full text

Combined activity of temozolomide and the <scp>mTOR</scp> inhibitor temsirolimus in metastatic melanoma involves DKK1

Heike Niessner, Corinna Kosnopfel, Tobias Sinnberg et al. · Experimental Dermatology · 2017 · 15 citations

Combined Activity, Immunology, Mtor Pathway +17