REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants

Nilah M. Ioannidis, Joseph H. Rothstein, Vikas Pejaver, +38

The American Journal of Human Genetics

Genome-wide Association StudyAllelic VariantGenotype-phenotype AssociationMedicineGenetics +12

Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase

Saswata Talukdar, Da Young Oh, Gautam Bandyopadhyay, +11

Nature Medicine

InflammationMetabolic SyndromeBiochemistryLipid NutritionDiabetes +7

Evidence for a prostate cancer susceptibility locus on the X chromosome.

Jianfeng Xu, Deborah Meyers, Diha Freije, +40

Nature Genetics

UrologyCytogeneticsX ChromosomeGeneticsChromosome Biology +3

Adipocyte NCoR Knockout Decreases PPARγ Phosphorylation and Enhances PPARγ Activity and Insulin Sensitivity

Pingping Li, WuQiang Fan, Jianfeng Xu, +12

Cell

Energy HomeostasisInsulin SensitivityMolecular PhysiologySignal TransductionBiochemistry +9

HOTTIP lncRNA Promotes Hematopoietic Stem Cell Self-Renewal Leading to AML-like Disease in Mice

Huacheng Luo, Ganqian Zhu, Jianfeng Xu, +16

Cancer Cell

Developmental BiologyAml-like DiseaseMedicineHematologyStem Cell Research +6

NCoR Repression of LXRs Restricts Macrophage Biosynthesis of Insulin-Sensitizing Omega 3 Fatty Acids

Pingping Li, Nathanael J. Spann, Minna U. Kaikkonen, +15

Cell

Metabolic SyndromeSignal TransductionBiochemistryFatty AcidsNatural Sciences +11

Homeobox oncogene activation by pan-cancer DNA hypermethylation

Jianzhong Su, Yung‐Hsin Huang, Xiaodong Cui, +9

Genome biology

Role of PKC and MAPK in cytosolic PLA₂ phosphorylation and arachadonic acid release in primary murine astrocytes

Jianfeng Xu, Yu‐I Weng, Agnes Simoni, +4

Journal of Neurochemistry

Prostaglandin E2 production in astrocytes: regulation by cytokines, extracellular ATP, and oxidative agents

Jianfeng Xu, Małgorzata Chalimoniuk, Yilong Shu, +6

Prostaglandins Leukotrienes and Essential Fatty Acids

Extracellular AtpSignal TransductionEpendymaGliomaCell Signaling +13

Linkage of prostate cancer susceptibility loci to chromosome 1

Jianfeng Xu, Siqun L. Zheng, Bao-Li Chang, +13

Human Genetics

UrologyGeneticsGenetic EpidemiologyCancer GenomicsProstatic Disease +3