The RNA m6A Reader YTHDF2 Maintains Oncogene Expression and Is a Targetable Dependency in Glioblastoma Stem Cells

Deobrat Dixit, Briana C. Prager, Ryan C. Gimple, +17

Cancer Discovery

Targeting glioma stem cells through combined BMI1 and EZH2 inhibition

Xun Jin, Leo J.Y. Kim, Qiulian Wu, +14

Nature Medicine

Neuro-oncologyNovel TherapyGliomaMedicineGlioma Stem Cells +10

N-methyladenine DNA Modification in Glioblastoma

Qi Xie, Tao Wu, Ryan C. Gimple, +26

Cell

Reciprocal Signaling between Glioblastoma Stem Cells and Differentiated Tumor Cells Promotes Malignant Progression

Xiuxing Wang, Briana C. Prager, Qiulian Wu, +26

Cell stem cell

Neuro-oncologyLineage PlasticityGlioblastoma Stem CellsGliomaMedicine +7

Targeting Glioblastoma Stem Cells through Disruption of the Circadian Clock

Zhen Dong, Guoxin Zhang, Meng Qu, +17

Cancer Discovery

Therapeutic targeting of ependymoma as informed by oncogenic enhancer profiling

Stephen C. Mack, Kristian W. Pajtler, Lukas Chávez, +72

Nature

OncologyNovel TherapyOncogenic AgentMedicinePathology +5

Purine synthesis promotes maintenance of brain tumor initiating cells in glioma

Xiuxing Wang, Kailin Yang, Qi Xie, +19

Nature Neuroscience

Neuro-oncologyPurine SynthesisEndocrine OncologyTumor InnervationGlioma +6

Transcription elongation factors represent in vivo cancer dependencies in glioblastoma

Tyler E. Miller, Brian B. Liau, Lisa C. Wallace, +21

Nature

Neuro-oncologyTranscriptional RegulationGliomaMedicineCancer Genomics +8

Targeting pyrimidine synthesis accentuates molecular therapy response in glioblastoma stem cells

Xiuxing Wang, Kailin Yang, Qiulian Wu, +18

Science Translational Medicine

Zika Virus Targets Glioblastoma Stem Cells through a SOX2-Integrin αvβ5 Axis

Zhe Zhu, Pinar Mesci, Jean Bernatchez, +31

Cell stem cell

GliomaViral PathogenesisImmunologyVirologySox2-integrin αVβ5 Axis +4