Joana Gigante

Endothelial Jagged1 Antagonizes Dll4 Regulation of Endothelial Branching and Promotes Vascular Maturation Downstream of Dll4/Notch1

Ana‐Rita Pedrosa, Alexandre Trindade, Ana-Carina Fernandes et al. · Arteriosclerosis Thrombosis and Vascular Biology · 2015 · 132 citations · Full text

Combination of Dll4/Notch and Ephrin-B2/EphB4 targeted therapy is highly effective in disrupting tumor angiogenesis

D. Djokovic, Alexandre Trindade, Joana Gigante et al. · BMC Cancer · 2010 · 92 citations · Full text

Low-Dosage Inhibition of Dll4 Signaling Promotes Wound Healing by Inducing Functional Neo-Angiogenesis

Alexandre Trindade, D. Djokovic, Joana Gigante et al. · PLoS ONE · 2012 · 39 citations · Full text

Inflammation, Tumor Hypoxia, Angiogenesis +15

Metastasis is impaired by endothelial-specific Dll4 loss-of-function through inhibition of epithelial-to-mesenchymal transition and reduction of cancer stem cells and circulating tumor cells

Alexandre Trindade, Catarina Carvalho, Jorge Correia et al. · Clinical & Experimental Metastasis · 2019 · 30 citations

Tumor Biology, Epithelial-to-mesenchymal Transition, Medicine +10

Endothelial Dll4 overexpression reduces vascular response and inhibits tumor growth and metastasization in vivo

Alexandre Trindade, D. Djokovic, Joana Gigante et al. · BMC Cancer · 2017 · 28 citations · Full text