Concepedia

Combination of Dll4/Notch and Ephrin-B2/EphB4 targeted therapy is highly effective in disrupting tumor angiogenesis

D. Djokovic, Alexandre Trindade, Joana Gigante, Marina Badenes, Lilliana Silva, Ren Liu, Xiu‐Qing Li, Ming Gong, Valery Krasnoperov, Parkash S. Gill,

BMC Cancer · 2010 · 92 citations · 34 references

DOIFull text

Open access

Abstract

Combination targeting of Dll4/Notch and Ephrin-B2/EphB4 has potential for clinical investigation, providing cumulative efficacy and increased safety over Dll4/Notch inhibition alone.

References

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Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors

Gabriele Bergers, Steven Song, Nicole Meyer-Morse et al. · Journal of Clinical Investigation · 2003 · 1.2K citations · Full text

Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors

Gabriele Bergers, Steven Song, Nicole Meyer-Morse et al. · Journal of Clinical Investigation · 2003 · 1.2K citations

, , +19