Induction of p21 (WAF-1/CIP1) during differentiation.

Richard A. Steinman, Barbara Hoffman, A Iro, +3

PubMed

Induction of bax by genotoxic stress in human cells correlates with normal p53 status and apoptosis.

Qimin Zhan, Sajan Fan, Insoo Bae, +4

PubMed

p53 involvement in control of G2 exit of the cell cycle: role in DNA damage-induced apoptosis.

Christel Guillouf, Filippo Rosselli, Kandasamy Krishnaraju, +3

PubMed

Hypomutability in Fanconi anemia cells is associated with increased deletion frequency at the HPRT locus.

D. Papadopoulo, Christel Guillouf, H.W. Mohrenweiser, +1

Proceedings of the National Academy of Sciences

Hprt LocusIncreased Deletion FrequencyGenome InstabilityFanconi Anemia CellsFanconi Anemia +11

Dissection of the genetic programs of p53-mediated G1 growth arrest and apoptosis: blocking p53-induced apoptosis unmasks G1 arrest

Christel Guillouf, Xavier Graña, Muthu Selvakumaran, +4

Blood

Deregulated apoptosis is a hallmark of the Fanconi anemia syndrome.

A Ridet, Christel Guillouf, Éric Duchaud, +4

PubMed

Fanconi AnemiaGenome InstabilityBone Marrow FailureFa SyndromeMalignant Blood Disorder +9

Nebula—a web-server for advanced ChIP-seq data analysis

Valentina Boeva, Alban Lermine, Camille Barette, +2

Bioinformatics

Spi-1/PU.1 Oncogene Accelerates DNA Replication Fork Elongation and Promotes Genetic Instability in the Absence of DNA Breakage

Pauline Rimmelé, Jun Komatsu, Philippe Hupé, +7

Cancer Research

ChromatinGenome InstabilityPromotes Genetic InstabilityDna BreakageSomatic Variant +13

Epigenetic silencing of Bim transcription by Spi-1/PU.1 promotes apoptosis resistance in leukaemia

Maya Ridinger-Saison, Emilie Evanno, Isabelle Gallais, +5

Cell Death and Differentiation

Epigenetic SilencingChromatinSpi-1/pu.1 PromotesMixed-phenotype Acute LeukemiaGenetics +9

A Recurrent Activating Missense Mutation in Waldenström Macroglobulinemia Affects the DNA Binding of the ETS Transcription Factor SPI1 and Enhances Proliferation

Damien Roos‐Weil, Camille Decaudin, Marine Armand, +33

Cancer Discovery