Xavier Graña

Cell cycle control in mammalian cells: role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors (CKIs).

Xavier Graña, E. Premkumar Reddy · PubMed · 1995 · 1.1K citations

Life Sciences, Cell Biology, Molecular Biology +17

PITALRE, a nuclear CDC2-related protein kinase that phosphorylates the retinoblastoma protein in vitro.

Xavier Graña, Antonio De Luca, Nianli Sang et al. · Proceedings of the National Academy of Sciences · 1994 · 236 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Cloning of a new member of the retinoblastoma gene family (pRb2) which binds to the E1A transforming domain.

Xavier Mayol, Xavier Graña, Alfonso Baldi et al. · PubMed · 1993 · 229 citations

Life Sciences, Genetics, Molecular Biology +7

Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer

Hanghang Zhang, Somnath Pandey, Meghan Travers et al. · Cell · 2018 · 228 citations · Full text

Life Sciences, Molecular Biology, Oncology +12

The Ability of Positive Transcription Elongation Factor b To Transactivate Human Immunodeficiency Virus Transcription Depends on a Functional Kinase Domain, Cyclin T1, and Tat

Koh Fujinaga, Thomas P. Cujec, Junmin Peng et al. · Journal of Virology · 1998 · 160 citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +17