Muthu Selvakumaran

Immediate early up-regulation of bax expression by p53 but not TGF beta 1: a paradigm for distinct apoptotic pathways.

Muthu Selvakumaran, Hsueh Kung Lin, Toshiyuki Miyashita et al. · PubMed · 1994 · 483 citations

Life Sciences, Cancer Biology, Cell Biology +14

Enhanced cisplatin cytotoxicity by disturbing the nucleotide excision repair pathway in ovarian cancer cell lines.

Muthu Selvakumaran, Debra Pisarcik, Rudi Bao et al. · PubMed · 2003 · 316 citations

Medicine, Molecular Biology, Oncology +14

Autophagy Inhibition Sensitizes Colon Cancer Cells to Antiangiogenic and Cytotoxic Therapy

Muthu Selvakumaran, Ravi K. Amaravadi, Irina A. Vasilevskaya et al. · Clinical Cancer Research · 2013 · 221 citations · Full text

Medicine, Oncology, Pharmacology +17

The novel primary response gene MyD118 and the proto-oncogenes myb, myc, and bcl-2 modulate transforming growth factor beta 1-induced apoptosis of myeloid leukemia cells.

Muthu Selvakumaran, Hsueh‐Kung Lin, Robert Tjin Tham Sjin et al. · Molecular and Cellular Biology · 1994 · 185 citations · Full text

Life Sciences, Cell Biology, Oncology +17

The phosphatidylinositol 3-kinase/AKT signal transduction pathway plays a critical role in the expression of p21WAF1/CIP1/SDI1 induced by cisplatin and paclitaxel.

Yasuhiro Mitsuuchi, Steven W. Johnson, Muthu Selvakumaran et al. · PubMed · 2000 · 138 citations

Life Sciences, Cell Biology, Oncology +17