Jamie B. Spangler - Concepedia

Author

Jamie B. Spangler

Also Known As

J.B. Spangler, Jamie B Spangler, Jamie B. Spangler, Jamie Spangler, Jamie B. Spangler, Manzari, Mandana T., Spangler, Jamie

126

Publications

3.3K

Citations

H-Index

Concepts

All Affiliations

Johns Hopkins University Johns Hopkins Medicine Sidney Kimmel Comprehensive Cancer Center Bloomberg (United States)Stanford University

About

Jamie B. Spangler is an author at Johns Hopkins University specializing in medicine, immunology, and cell biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	15	17	1.6K
2	Engineering	6	6	221
3	Biomedical Engineering	4	4	183
4	Natural Sciences	3	3	80
5	Biochemistry	2	2	44

Jamie B. Spangler

Publications

2.3K

Citations

H-Index

Page 1

	Year	Citations
De novo design of potent and selective mimics of IL-2 and IL-15 Daniel‐Adriano Silva, Shawn Yu, Umut Y. Ulge, Nature CytokineMedicineSelective MimicsImmunologyImmunologic Mechanism	2019	524
Antibodies to Interleukin-2 Elicit Selective T Cell Subset Potentiation through Distinct Conformational Mechanisms Jamie B. Spangler, Jakub Tomala, Vincent C. Luca, Immunity InflammationDistinct Conformational MechanismsAutoimmune DiseaseAdaptive Immune SystemT-regulatory Cell	2015	214
Interleukin-2 Activity Can Be Fine Tuned with Engineered Receptor Signaling Clamps Suman Mitra, Aaron M. Ring, Shoba Amarnath, Immunity InflammationCytokineMolecular ImmunologySignal TransductionImmune Regulation	2015	174
Structural basis for IL-12 and IL-23 receptor sharing reveals a gateway for shaping actions on T versus NK cells Caleb R. Glassman, Yamuna Kalyani Mathiharan, Kevin M. Jude, Cell Autoimmune DiseaseIl-23 ReceptorT-regulatory CellImmune RegulationImmunology	2021	167
Combination antibody treatment down-regulates epidermal growth factor receptor by inhibiting endosomal recycling Jamie B. Spangler, Jason R. Neil, Sivan Abramovitch, Proceedings of the National Academy of Sciences	2010	154
Designed endocytosis-inducing proteins degrade targets and amplify signals Buwei Huang, Mohamad H. Abedi, Green Ahn, Nature	2024	97
Suspendable Hydrogel Nanovials for Massively Parallel Single-Cell Functional Analysis and Sorting Joseph de Rutte, Robert Dimatteo, Maani M. Archang, ACS Nano EngineeringPolyelectrolyte GelSingle CellsBiofabricationFlow Cell	2022	89
A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy Alfredo Quijano‐Rubio, M. Aladdin Bhuiyan, Huilin Yang, Nature Biotechnology	2022	70
Synthekines are surrogate cytokine and growth factor agonists that compel signaling through non-natural receptor dimers Ignacio Moraga, Jamie B. Spangler, Juan L. Mendoza, eLife ImmunologyImmune RegulationImmunologic MechanismInnate ImmunityReceptor Dimer Pairings	2017	67
Engineering a Single-Agent Cytokine/Antibody Fusion That Selectively Expands Regulatory T Cells for Autoimmune Disease Therapy Jamie B. Spangler, Eleonora Trotta, Jakub Tomala, The Journal of Immunology	2018	66

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