Vincent C. Luca

Intratumoural heterogeneity generated by Notch signalling promotes small-cell lung cancer

Jing Shan Lim, Alvaro Ibaseta, Marcus Fischer et al. · Nature · 2017 · 482 citations · Full text

Medicine, Intratumoural Heterogeneity, Radiation Oncology +5

Non-equivalence of Wnt and R-spondin ligands during Lgr5+ intestinal stem-cell self-renewal

Kelley S. Yan, Claudia Y. Janda, Junlei Chang et al. · Nature · 2017 · 467 citations · Full text

Developmental Biology, Medicine, Adult Stem Cell +5

Progenitor identification and SARS-CoV-2 infection in human distal lung organoids

Ameen A. Salahudeen, S. S. Choi, Arjun Rustagi et al. · Nature · 2020 · 406 citations · Full text

Respiratory Diseases, Progenitor Identification, Pathology +5

Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity

Vincent C. Luca, Byoung Choul Kim, Chenghao Ge et al. · Science · 2017 · 293 citations · Full text

Structural basis for Notch1 engagement of Delta-like 4

Vincent C. Luca, Kevin M. Jude, Nathan W. Pierce et al. · Science · 2015 · 267 citations · Full text