John S. Sack

Three-dimensional structure of calmodulin

Y.S. Babu, John S. Sack, Trevor J. Greenhough et al. · Nature · 1985 · 1K citations

Crystal Structure, Biochemistry, Three-dimensional Structure +6

Crystallographic structures of the ligand-binding domains of the androgen receptor and its T877A mutant complexed with the natural agonist dihydrotestosterone

John S. Sack, Kevin Kish, Chihuei Wang et al. · Proceedings of the National Academy of Sciences · 2001 · 483 citations · Full text

CHAIN — A crystallographic modeling program

John S. Sack · Journal of Molecular Graphics · 1988 · 339 citations

Crystal Structure, Engineering, Molecular Biology +7

Discovery of <i>N</i>-(4-(2-Amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (BMS-777607), a Selective and Orally Efficacious Inhibitor of the Met Kinase Superfamily

Gretchen M. Schroeder, Yongmi An, Zhen‐Wei Cai et al. · Journal of Medicinal Chemistry · 2009 · 276 citations · Full text

Orally Efficacious Inhibitor, Drug Target, Pharmacotherapy +21

<i>N</i>-(Cycloalkylamino)acyl-2-aminothiazole Inhibitors of Cyclin-Dependent Kinase 2. <i>N</i>-[5-[[[5-(1,1-Dimethylethyl)-2-oxazolyl]methyl]thio]-2-thiazolyl]-4- piperidinecarboxamide (BMS-387032), a Highly Efficacious and Selective Antitumor Agent

Raj N. Misra, Hai‐Yun Xiao, Kyoung S. Kim et al. · Journal of Medicinal Chemistry · 2004 · 251 citations · Full text

Chemoprevention Strategy, Immunology, Pharmacotherapy +19