The zebrafish dorsal axis is apparent at the four-cell stage

Aniket V. Gore, S. Maegawa, Albert Cheong, +3

Nature

BiologyZebrafish Dorsal AxisDevelopmental BiologyEpendymaMorphogenesis +6

TG02, a novel oral multi-kinase inhibitor of CDKs, JAK2 and FLT3 with potent anti-leukemic properties

K C Goh, Veronica Novotny‐Diermayr, Stefan Hart, +13

Leukemia

MedicineReceptor Tyrosine KinaseMalignant Blood DisorderImmunologyPotent Anti-leukemic Properties +7

Pacritinib (SB1518), a JAK2/FLT3 inhibitor for the treatment of acute myeloid leukemia

Stefan Hart, K. C. Goh, Veronica Novotny‐Diermayr, +9

Blood Cancer Journal

ImmunologyPharmacotherapyTumor BiologyMyeloid NeoplasiaHematological Malignancy +15

The oral HDAC inhibitor pracinostat (SB939) is efficacious and synergistic with the JAK2 inhibitor pacritinib (SB1518) in preclinical models of AML

Veronica Novotny‐Diermayr, Stefan Hart, K C Goh, +7

Blood Cancer Journal

Mixed-phenotype Acute LeukemiaImmunologyCell DeathPharmacotherapyTumor Biology +18

VS-5584, a Novel and Highly Selective PI3K/mTOR Kinase Inhibitor for the Treatment of Cancer

Stefan Hart, Veronica Novotny‐Diermayr, Kee Chuan Goh, +19

Molecular Cancer Therapeutics

Cancer BiologyTumor BiologyMolecular PharmacologyOncologyPi3k/mtor Pathway +14

p80 ROKα binding protein is a novel splice variant of CRMP‐1 which associates with CRMP‐2 and modulates RhoA‐induced neuronal morphology

Thomas Leung, Yvonne Ng, Albert Cheong, +4

FEBS Letters

Brain ExtractsCellular NeurobiologySocial SciencesSignaling PathwayReceptor Tyrosine Kinase +16

PC‐3 cells with enhanced androgen receptor signaling: A model for clonal selection in prostate cancer

Grant Buchanan, Paul Craft, Miao Yang, +5

The Prostate

Conservation defines functional motifs in the squint/nodal-related 1 RNA dorsal localization element

Patrick Gilligan, Pooja Kumari, Shimin Lim, +3

Nucleic Acids Research

A Novel Androgen Receptor Amino Terminal Region Reveals Two Classes of Amino/Carboxyl Interaction-Deficient Variants with Divergent Capacity to Activate Responsive Sites in Chromatin

Eleanor F. Need, Howard I. Scher, Amelia A. Peters, +7

Endocrinology

Genomic organization of human myotonic dystrophy kinase-related Cdc42-binding kinase α reveals multiple alternative splicing and functional diversity

Ivan Tan, Albert Cheong, Louis Lim, +1

Gene

Transcriptional RegulationSignal TransductionGenomic OrganizationSignaling PathwayFunctional Diversity +8