Massively Parallel Single-Cell RNA-Seq for Marker-Free Decomposition of Tissues into Cell Types

Diego Adhemar Jaitin, Ephraim Kenigsberg, Hadas Keren‐Shaul, +8

Science

Single-cell Hi-C reveals cell-to-cell variability in chromosome structure

Takashi Nagano, Yaniv Lubling, Tim J. Stevens, +6

Nature

ChromatinSingle Cell SequencingMedicineGeneticsSingle-cell Biology +5

Multiscale 3D Genome Rewiring during Mouse Neural Development

Boyan Bonev, Netta Mendelson Cohen, Quentin Szabo, +8

Cell

Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors

Franziska Paul, Ya’ara Arkin, Amir Giladi, +19

Cell

Developmental BiologyGeneticsTranscription RegulationLineage CommitmentGene Expression +4

Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma

Hanjie Li, Anne M. van der Leun, Ido Yofe, +15

Cell

Cancer ImmunosurveillanceHuman MelanomaT-regulatory CellMelanomaImmunology +6

Derivation of novel human ground state naive pluripotent stem cells

Ohad Gafni, Leehee Weinberger, Abed AlFatah Mansour, +24

Nature

Tissue EngineeringInduced Pluripotent Stem CellDevelopmental BiologyMedicineInduced Pluripotent Stem Cells +7

Discovering statistically significant biclusters in gene expression data

Amos Tanay, Roded Sharan, Ron Shamir

Bioinformatics

Prediction of acute myeloid leukaemia risk in healthy individuals

Sagi Abelson, Grace Collord, Stanley Ng, +72

Nature

Hematological MalignancyHealthy IndividualsMixed-phenotype Acute LeukemiaHematologyOncology +2

Cell-cycle dynamics of chromosomal organization at single-cell resolution

Takashi Nagano, Yaniv Lubling, Csilla Várnai, +7

Nature

ChromatinPattern FormationCell DivisionMedicineDna Replication +6

Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq

Diego Adhemar Jaitin, Assaf Weiner, Ido Yofe, +7

Cell

Functional GenomicsSingle Cell SequencingMedicineImmunologySingle-cell Genomics +7