Gunhild Jug

Among genes involved in the RB dependent cell cycle regulatory cascade, the p16 tumor suppressor gene is frequently lost in the Ewing family of tumors

Heinrich Kovar, Gunhild Jug, Dave N.T. Aryee et al. · Oncogene · 1997 · 152 citations

Cell Regulation, Medicine, Pathology +8

EWS/FLI-1 antagonists induce growth inhibition of Ewing tumor cells in vitro.

Heinrich Kovar, D N T Aryee, Gunhild Jug et al. · PubMed · 1996 · 149 citations

Ewing Tumor Cells, Neuroblastoma Cell Line, Immunology +18

Oncogenic ETS fusions deregulate E2F3 target genes in Ewing sarcoma and prostate cancer

Sven Bilke, Raphaela Schwentner, Fan Yang et al. · Genome Research · 2013 · 119 citations · Full text

Narrow spectrum of infrequent p53 mutations and absence of MDM2 amplification in Ewing tumours.

Heinrich Kovar, Annegret Auinger, Gunhild Jug et al. · PubMed · 1993 · 113 citations

EWS-FLI1 Suppresses NOTCH-Activated p53 in Ewing's Sarcoma

Jozef Ban, Idriss M. Bennani-Baı̈ti, Max Kauer et al. · Cancer Research · 2008 · 111 citations · Full text