Botensilimab plus balstilimab in relapsed/refractory microsatellite stable metastatic colorectal cancer: a phase 1 trial

Andrea J. Bullock, Benjamin L. Schlechter, Marwan Fakih, +25

Nature Medicine

Altered microtubule dynamics and vesicular transport in mouse and human MeCP2-deficient astrocytes

Chloé Delépine, Hamid Méziane, Juliette Nectoux, +12

Human Molecular Genetics

A low-cost 3D printed microfluidic bioreactor and imaging chamber for live-organoid imaging

Ikram Khan, Anil Prabhakar, Chloé Delépine, +3

Biomicrofluidics

Label-free three-photon imaging of intact human cerebral organoids for tracking early events in brain development and deficits in Rett syndrome

Chloé Delépine, Danielle Feldman, Vincent A. Pham, +7

eLife

EngineeringDevelopmental Cognitive NeuroscienceBrain DevelopmentRett SyndromeCerebral Organoid +26

Astrocyte Transcriptome from the Mecp2308-Truncated Mouse Model of Rett Syndrome

Chloé Delépine, Juliette Nectoux, Franck Letourneur, +4

NeuroMolecular Medicine

Molecular NeuroscienceDevelopmental BiologyMendelian DisorderGenetic DisorderGenetics +7

Botensilimab, an Fc-Enhanced Anti–CTLA-4 Antibody, Is Effective against Tumors Poorly Responsive to Conventional Immunotherapy

Dhan Chand, David A. Savitsky, Shanmugarajan Krishnan, +40

Cancer Discovery

Altered microtubule dynamics in Mecp2‐deficient astrocytes

Juliette Nectoux, Cédrick Florian, Chloé Delépine, +5

Journal of Neuroscience Research

Differential Effects of Astrocyte Manipulations on Learned Motor Behavior and Neuronal Ensembles in the Motor Cortex

Chloé Delépine, Jennifer Shih, Keji Li, +2

Journal of Neuroscience

MeCP2 deficiency is associated with impaired microtubule stability

Chloé Delépine, Juliette Nectoux, Nadia Bahi‐Buisson, +2

FEBS Letters

Cell PhysiologyMecp2 DeficiencyMolecular NeuroscienceDevelopmental BiologyBrain Development +13

GSK3ß inhibitor CHIR 99021 modulates cerebral organoid development through dose-dependent regulation of apoptosis, proliferation, differentiation and migration

Chloé Delépine, Vincent A. Pham, Hayley W. S. Tsang, +1

PLoS ONE

Organoid SizeLow DoseBrain DevelopmentDose-dependent RegulationApoptosis +24