Ruxandra Dafinca - Concepedia

Author

Ruxandra Dafinca

University of Oxford ORCID

Also Known As

R. Dafinca, Ruxandra Dafinca

Publications

1.1K

Citations

H-Index

Concepts

All Affiliations

University of Oxford John Radcliffe Hospital Oxford Research Group University of Jordan Chinese Academy of Medical Sciences & Peking Union Medical College

About

Ruxandra Dafinca is an author at University of Oxford specializing in neurodegenerative diseases, social sciences, and cell biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	3	3	493
2	Social Sciences	3	3	493
3	Cell Biology	3	3	493
4	Neuroscience	3	3	493
5	Neurology	2	2	389

Ruxandra Dafinca

Publications

985

Citations

H-Index

Page 1

	Year	Citations
<i>C9orf72</i> Hexanucleotide Expansions Are Associated with Altered Endoplasmic Reticulum Calcium Homeostasis and Stress Granule Formation in Induced Pluripotent Stem Cell-Derived Neurons from Patients with Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Ruxandra Dafinca, Jakub Scaber, Nidaa A. Ababneh, Stem Cells NeurogenomicsSporadic AlsStem Cells 2016Stress Granule FormationSynaptic Signaling	2016	238
C9orf72 and RAB7L1 regulate vesicle trafficking in amyotrophic lateral sclerosis and frontotemporal dementia Yoshitsugu Aoki, Raquel Manzano, Yi Lee, Brain Neurodegenerative DiseasesVesicle TraffickingNeurobiology Of DiseaseIntron 1Amyotrophic Lateral Sclerosis	2017	151
Axonal TDP-43 condensates drive neuromuscular junction disruption through inhibition of local synthesis of nuclear encoded mitochondrial proteins Topaz Altman, Ariel Ionescu, Amjad Ibraheem, Nature Communications	2021	132
Impairment of Mitochondrial Calcium Buffering Links Mutations in C9ORF72 and TARDBP in iPS-Derived Motor Neurons from Patients with ALS/FTD Ruxandra Dafinca, Paola Barbagallo, Lucy Farrimond, Stem Cell Reports	2020	127
Single-copy expression of an amyotrophic lateral sclerosis-linked TDP-43 mutation (M337V) in BAC transgenic mice leads to altered stress granule dynamics and progressive motor dysfunction David F. Gordon, Ruxandra Dafinca, Jakub Scaber, Neurobiology of Disease Bac Transgenic MiceNeurodegenerative DiseasesAmyotrophic Lateral SclerosisMolecular NeuroscienceStress Granule Dynamics	2018	104
Correction of amyotrophic lateral sclerosis related phenotypes in induced pluripotent stem cell-derived motor neurons carrying a hexanucleotide expansion mutation in C9orf72 by CRISPR/Cas9 genome editing using homology-directed repair Nidaa A. Ababneh, Jakub Scaber, Rowan Flynn, Human Molecular Genetics	2020	69
C9orf72-ALS human iPSC microglia are pro-inflammatory and toxic to co-cultured motor neurons via MMP9 Björn F. Vahsen, Sumedha Nalluru, Georgia R. Morgan, Nature Communications	2023	61
An ALS-linked mutation in TDP-43 disrupts normal protein interactions in the motor neuron response to oxidative stress Emily Feneberg, David F. Gordon, Alexander G. Thompson, Neurobiology of Disease	2020	41
Human iPSC co-culture model to investigate the interaction between microglia and motor neurons Björn F. Vahsen, Elizabeth Gray, Ana Candalija, Scientific Reports	2022	41
Poly(ADP-ribose) promotes toxicity of <i>C9ORF72</i> arginine-rich dipeptide repeat proteins Junli Gao, Quinlan T. Mewborne, Amandeep Girdhar, Science Translational Medicine	2022	21

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