Topaz Altman

Axonal TDP-43 condensates drive neuromuscular junction disruption through inhibition of local synthesis of nuclear encoded mitochondrial proteins

Topaz Altman, Ariel Ionescu, Amjad Ibraheem et al. · Nature Communications · 2021 · 132 citations · Full text

ALS Along the Axons – Expression of Coding and Noncoding RNA Differs in Axons of ALS models

Nimrod Rotem, Iddo Magen, Ariel Ionescu et al. · Scientific Reports · 2017 · 106 citations · Full text

Targeting the Sigma-1 Receptor via Pridopidine Ameliorates Central Features of ALS Pathology in a SOD1G93A Model

Ariel Ionescu, Tal Gradus, Topaz Altman et al. · Cell Death and Disease · 2019 · 86 citations · Full text

Localization of RNAi Machinery to Axonal Branch Points and Growth Cones Is Facilitated by Mitochondria and Is Disrupted in ALS

Noga Gershoni‐Emek, Topaz Altman, Ariel Ionescu et al. · Frontiers in Molecular Neuroscience · 2018 · 43 citations · Full text

The receptor tyrosine kinase TrkB signals without dimerization at the plasma membrane

Eitan Erez Zahavi, Noam Steinberg, Topaz Altman et al. · Science Signaling · 2018 · 35 citations

Monomeric Receptor, Trkb Homodimerization, Trkb Monomers +20