Metformin inhibits melanoma development through autophagy and apoptosis mechanisms

Tijana Tomić, Thomas Botton, Michaël Cerezo, +12

Cell Death and Disease

Tumor BiologyMitophagyCell AutophagyMetformin ActionCell Regulation +12

Compounds Triggering ER Stress Exert Anti-Melanoma Effects and Overcome BRAF Inhibitor Resistance

Michaël Cerezo, Abdelali Lehraiki, Antoine Millet, +27

Cancer Cell

MedicinePhotocarcinogenesisMelanomaAnti-cancer AgentDermatology +4

Translational control of tumor immune escape via the eIF4F–STAT1–PD-L1 axis in melanoma

Michaël Cerezo, Ramdane Guemiri, Sabine Druillennec, +19

Nature Medicine

Cancer ImmunosurveillanceEif4f–stat1–pd-l1 AxisMedicineMelanomaImmunology +10

Metformin Blocks Melanoma Invasion and Metastasis Development in AMPK/p53-Dependent Manner

Michaël Cerezo, Mélanie Tichet, Patricia Abbe, +10

Molecular Cancer Therapeutics

Ampk/p53-dependent MannerTumor BiologyOncologyMedicineMetformin Inhibits +12

Tumour-derived SPARC drives vascular permeability and extravasation through endothelial VCAM1 signalling to promote metastasis

Mélanie Tichet, Virginie Prod’homme, Nina Fenouille, +15

Nature Communications

The PRKAA1/AMPKα1 pathway triggers autophagy during CSF1-induced human monocyte differentiation and is a potential target in CMML

Sandrine Obba, Zoheir Hizir, Laurent Boyer, +19

Autophagy

ImmunologyCsf1-induced AutophagyCellular PhysiologyInflammationCell Autophagy +15

Autophagy Plays a Critical Role in the Degradation of Active RHOA, the Control of Cell Cytokinesis, and Genomic Stability

Amine Belaïd, Michaël Cerezo, Abderrahman Chargui, +14

Cancer Research

MitophagyCell CytokinesisImmunologyPathologyCancer Biology +20

Pivotal role of NAMPT in the switch of melanoma cells toward an invasive and drug-resistant phenotype

Mickaël Ohanna, Michaël Cerezo, Nicolas Nottet, +8

Genes & Development

New anti-cancer molecules targeting HSPA5/BIP to induce endoplasmic reticulum stress, autophagy and apoptosis

Michaël Cerezo, Stéphane Rocchi

Autophagy

MitophagyMelanoma TreatmentApoptosisImmunologyCell Death +16

Inhibition of Melanogenesis by the Antidiabetic Metformin

Abdelali Lehraiki, Patricia Abbe, Michaël Cerezo, +7

Journal of Investigative Dermatology

MedicineInsulin ManagementDiabetesGlycobiologyAntidiabetic Metformin +4