Thomas Botton

CNVkit: Genome-Wide Copy Number Detection and Visualization from Targeted DNA Sequencing

Eric Talevich, A. Hunter Shain, Thomas Botton et al. · PLoS Computational Biology · 2016 · 2.2K citations · Full text

Engineering, Genetics, Molecular Biology +19

Kinase fusions are frequent in Spitz tumours and spitzoid melanomas

Thomas Wiesner, Jie He, Roman Yelensky et al. · Nature Communications · 2014 · 621 citations · Full text

Tumor Biology, Medicine, Receptor Tyrosine Kinase +7

Metformin inhibits melanoma development through autophagy and apoptosis mechanisms

Tijana Tomić, Thomas Botton, Michaël Cerezo et al. · Cell Death and Disease · 2011 · 294 citations · Full text

Tumor Biology, Mitophagy, Cell Autophagy +14

Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway

A. Hunter Shain, M Garrido, Thomas Botton et al. · Nature Genetics · 2015 · 279 citations · Full text

Tumor Biology, Tumor Heterogeneity, Exome Sequencing +11

Compounds Triggering ER Stress Exert Anti-Melanoma Effects and Overcome BRAF Inhibitor Resistance

Michaël Cerezo, Abdelali Lehraiki, Antoine Millet et al. · Cancer Cell · 2016 · 251 citations · Full text

Medicine, Photocarcinogenesis, Melanoma +6