Molecular Basis of AKAP Specificity for PKA Regulatory Subunits

Matthew G. Gold, Birgitte Lygren, P. Dokurno, +6

Molecular Cell

Protein FunctionSignal TransductionMolecular PhysiologyMolecular RegulationNatural Sciences +7

AKAP complex regulates Ca ²⁺ re‐uptake into heart sarcoplasmic reticulum

Birgitte Lygren, Cathrine R. Carlson, Katja Santamaria, +8

EMBO Reports

Cardiac MuscleHeart Sarcoplasmic ReticulumMolecular PhysiologySignal TransductionPhysiology +9

Delineation of Type I Protein Kinase A-selective Signaling Events Using an RI Anchoring Disruptor

Cathrine R. Carlson, Birgitte Lygren, Torunn Berge, +4

Journal of Biological Chemistry

Molecular BiologyCamp SignalingType Ii PkaSignaling PathwayCell Regulation +14

An entirely specific type I A-kinase anchoring protein that can sequester two molecules of protein kinase A at mitochondria

Christopher K. Means, Birgitte Lygren, Lorene K. Langeberg, +11

Proceedings of the National Academy of Sciences

In resting COS1 cells a dominant negative approach shows that specific, anchored PDE4 cAMP phosphodiesterase isoforms gate the activation, by basal cyclic AMP production, of AKAP-tethered protein kinase A type II located in the centrosomal region

Angela McCahill, Theresa McSorley, Elaine Huston, +7

Cellular Signalling

Cos1 CellsMolecular PhysiologySignal TransductionBiochemistrySignaling Pathway +10

A PKA-ezrin-connexin 43 signaling complex controls gap junction communication and thereby trophoblast cell fusion

Guillaume Pidoux, Pascale Gerbaud, Jim Dompierre, +4

Journal of Cell Science

Dual Specificity A-kinase Anchoring Proteins (AKAPs) Contain an Additional Binding Region That Enhances Targeting of Protein Kinase A Type I

Elisabeth Jarnæss, Anja Ruppelt, Anne Jorunn Stokka, +3

Journal of Biological Chemistry

Molecular BiologyA-kinase Anchoring ProteinsSignaling PathwayCell RegulationReceptor Tyrosine Kinase +14

Positional cloning identifies a novel cyclophilin as a candidate amplified oncogene in 1q21

Leonardo A. Meza‐Zepeda, Anne Forus, Birgitte Lygren, +15

Oncogene

Novel CyclophilinNatural SciencesProtein BiosynthesisMolecular BiologyDna Replication +4

Both El Tor and classical cholera toxin bind blood group determinants

Julie E. Heggelund, Espen Haugen, Birgitte Lygren, +6

Biochemical and Biophysical Research Communications

Microbial ToxinToxinologyVirulence FactorEl TorPathogenesis +6

The adaptor protein EBP50 is important for localization of the protein kinase A–Ezrin complex in T-cells and the immunomodulating effect of cAMP

Anne Jorunn Stokka, Randi Mosenden, Anja Ruppelt, +2

Biochemical Journal

ImmunologyCellular PhysiologyEzrin-ebp50 InteractionSignaling PathwayCell Regulation +14