Thomas P. Corner

The selective prolyl hydroxylase inhibitor IOX5 stabilizes HIF-1α and compromises development and progression of acute myeloid leukemia

Hannah Lawson, James P. Holt‐Martyn, Vilma Dembitz et al. · Nature Cancer · 2024 · 41 citations · Full text

Medicine, Hematology, Pharmacology +16

Kinetic and inhibition studies on human Jumonji-C (JmjC) domain-containing protein 5

Anthony Tumber, E. Salah, Lennart Brewitz et al. · RSC Chemical Biology · 2023 · 15 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +8

Structure-guided optimisation of <i>N</i>-hydroxythiazole-derived inhibitors of factor inhibiting hypoxia-inducible factor-α

Thomas P. Corner, Yue Wu, E. Salah et al. · Chemical Science · 2023 · 14 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

5-Substituted Pyridine-2,4-dicarboxylate Derivatives Have Potential for Selective Inhibition of Human Jumonji-C Domain-Containing Protein 5

Lennart Brewitz, Yu Nakashima, Sonia K. Piasecka et al. · Journal of Medicinal Chemistry · 2023 · 12 citations · Full text

Life Sciences, Biochemistry, Pharmacology +13