Concepedia

James P. Holt‐Martyn

JP

6

Publications

391

Citations

6

H-Index

2015

Active since

Affiliations

University of Oxford(Current)

University of Toyama

The Francis Crick Institute

James P. Holt‐Martyn is an author at University of Oxford specializing in medicinal chemistry, drug discovery, and natural sciences.

ORCID

Top concepts

Publications per year

2015–2024

6

Publications

6

Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials

Tzu‐Lan Yeh, T.M. Leissing, Martine I. Abboud et al. · Chemical Science · 2017 · 219 citations · Full text

Potent and Selective Triazole-Based Inhibitors of the Hypoxia-Inducible Factor Prolyl-Hydroxylases with Activity in the Murine Brain

Mun Chiang Chan, Onur Atasoylu, Emma J. Hodson et al. · PLoS ONE · 2015 · 65 citations · Full text

, , +22

Structural Basis of Prolyl Hydroxylase Domain Inhibition by Molidustat

William D. Figg, M.A. McDonough, Rasheduzzaman Chowdhury et al. · ChemMedChem · 2021 · 33 citations · Full text

The selective prolyl hydroxylase inhibitor IOX5 stabilizes HIF-1α and compromises development and progression of acute myeloid leukemia

Hannah Lawson, James P. Holt‐Martyn, Vilma Dembitz et al. · Nature Cancer · 2024 · 32 citations · Full text

Structure‐Activity Relationship and Crystallographic Studies on 4‐Hydroxypyrimidine HIF Prolyl Hydroxylase Domain Inhibitors

James P. Holt‐Martyn, Rasheduzzaman Chowdhury, Anthony Tumber et al. · ChemMedChem · 2019 · 29 citations · Full text

, , +18

Rows per page

1–5 of 6