TRPV1 Involvement in Inflammatory Tissue Fibrosis in Mice

Yuka Okada, Peter S. Reinach, Kumi Shirai, +7

American Journal Of Pathology

InflammationFibrosisAutoimmune DiseaseMedicineImmune Regulation +4

TRPA1 is required for TGF-β signaling and its loss blocks inflammatory fibrosis in mouse corneal stroma

Yuka Okada, Kumi Shirai, Peter S. Reinach, +6

Laboratory Investigation

InflammationFibrosisSignal TransductionMolecular PhysiologyOphthalmology +7

Impairment of Corneal Epithelial Wound Healing in a TRPV1-Deficient Mouse

Takayoshi Sumioka, Yuka Okada, Peter S. Reinach, +4

Investigative Ophthalmology & Visual Science

Accumulation of latent transforming growth factor-β binding protein-1 and TGFβ1 in extracellular matrix of filtering bleb and of cultured human subconjunctival fibroblasts

Shizuya Saika, Osamu Yamanaka, Yukio Baba, +6

Graefe s Archive for Clinical and Experimental Ophthalmology

FibrosisDevelopmental BiologySignal TransductionFibroblast Growth FactorCell Proliferation +7

Sensory nerve supports epithelial stem cell function in healing of corneal epithelium in mice: the role of trigeminal nerve transient receptor potential vanilloid 4

Yuka Okada, Takayoshi Sumioka, Kana Ichikawa, +15

Laboratory Investigation

Regenerative MedicineOphthalmologyCorneal DystrophyMedicineOcular Tissue +6

Emodin Suppression of Ocular Surface Inflammatory Reaction

Ai Kitano, Shizuya Saika, Osamu Yamanaka, +4

Investigative Ophthalmology & Visual Science

Loss of TRPV4 Function Suppresses Inflammatory Fibrosis Induced by Alkali-Burning Mouse Corneas

Yuka Okada, Kumi Shirai, Masayasu Miyajima, +6

PLoS ONE

Acute Lung InjuryInflammatory Lung DiseaseLung InflammationImmunologyImmune Regulation +22

A new model of anterior subcapsular cataract: involvement of TGFbeta/Smad signaling.

Kumi Shirai, Shizuya Saika, Takeshi Tanaka, +4

PubMed

Genipin Suppresses Subconjunctival Fibroblast Migration, Proliferation and Myofibroblast Transdifferentiation

Ai Kitano, Shizuya Saika, Osamu Yamanaka, +6

Ophthalmic Research

Loss of osteopontin perturbs the epithelial-mesenchymal transition in an injured mouse lens epithelium

Shizuya Saika, Kumi Shirai, Osamu Yamanaka, +10

Laboratory Investigation

Regenerative MedicineEpithelial-mesenchymal TransitionDevelopmental BiologyOphthalmologyBone Morphogenic Protein +7