Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia

Panagiotis Ntziachristos, Aristotelis Tsirigos, G. Grant Welstead, +23

Nature

Histone ModificationsChromatinTumor BiologyAcute Lymphoblastic LeukaemiaHematological Malignancy +12

Regulation of Pluripotency and Cellular Reprogramming by the Ubiquitin-Proteasome System

Shannon M. Buckley, Beatriz Aranda-Orgillés, Alexandros Strikoudis, +11

Cell stem cell

Protein FunctionCell RegulationCell DivisionMolecular RegulationMedicine +9

Modeling of Fibrotic Lung Disease Using 3D Organoids Derived from Human Pluripotent Stem Cells

Alexandros Strikoudis, Anna Cieślak, Lucas F. Loffredo, +5

Cell Reports

Therapeutic Targeting of the Cyclin D3:CDK4/6 Complex in T Cell Leukemia

Catherine M. Sawai, Jacquelyn Freund, Philmo Oh, +9

Cancer Cell

Hematological MalignancyMedicineMalignant Blood DisorderImmunologyT Cell Leukemia +6

Harnessing Hematopoietic Stem Cell Low Intracellular Calcium Improves Their Maintenance In Vitro

Larry L. Luchsinger, Alexandros Strikoudis, Nichole Danzl, +6

Cell stem cell

Developmental BiologyMedicineStem Cell MobilizationAdult Stem CellHematology +7

USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia

Qi Jin, Carlos A. Martínez, Kelly M. Arcipowski, +44

Clinical Cancer Research

Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a

Alexandros Strikoudis, Charalampos Lazaris, Thomas Trimarchi, +11

Nature Cell Biology

Transcriptional RegulationDevelopmental BiologyCell RegulationTranscriptional ElongationPhd-finger Protein Phf5a +5

The CUL4-DDB1 ubiquitin ligase complex controls adult and embryonic stem cell differentiation and homeostasis

Jie Gao, Shannon M. Buckley, Luisa Cimmino, +5

eLife

ChromatinTranscriptional RegulationCell LineageDevelopmental BiologyCell Regulation +13

PRDM16 isoforms differentially regulate normal and leukemic hematopoiesis and inflammatory gene signature

David Corrigan, Larry L. Luchsinger, Mariana Justino de Almeida, +3

Journal of Clinical Investigation

Mixed-phenotype Acute LeukemiaImmunologyPathologyLeukemic HematopoiesisMyeloid Neoplasia +17

Glycogen synthase kinase 3 induces multilineage maturation of human pluripotent stem cell-derived lung progenitors in 3D culture

Ana Luísa Rodrigues Toste de Carvalho, Alexandros Strikoudis, Hsiao‐Yun Liu, +5

Development