Matthew J. Saabye - Concepedia

Concepedia

Author

Matthew J. Saabye

Pfizer (United States)

Also Known As

Matthew J Saabye, Matthew J. Saabye, Matthew Saabye

11

Publications

1.2K

Citations

11

H-Index

17

Concepts

All Affiliations

Pfizer (United States)Confluence Life Sciences (United States)

MJ

About

Matthew J. Saabye is an author at Pfizer (United States) specializing in medicine, cell signaling, and signal transduction.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	4	4	385
2	Natural Sciences	3	3	111
3	Biochemistry	3	3	111
4	Cell Biology	2	2	295
5	Cellular Physiology	2	2	295

Matthew J. Saabye

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11

Publications

1.2K

Citations

11

H-Index

	Year	Citations
Anti-inflammatory activity and neutrophil reductions mediated by the JAK1/JAK3 inhibitor, CP-690,550, in rat adjuvant-induced arthritis Debra M. Meyer, Michael I. Jesson, Xiong Li, Journal of Inflammation	2010	455
Modulation of cellular S1P levels with a novel, potent and specific inhibitor of sphingosine kinase-1 Mark E. Schnute, Matthew D. McReynolds, Tom Kasten, Biochemical Journal Specific InhibitorWhole BloodCellular PhysiologySignaling PathwayCell Regulation	2012	274
A Benzothiophene Inhibitor of Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 Inhibits Tumor Necrosis Factor α Production and Has Oral Anti-Inflammatory Efficacy in Acute and Chronic Models of Inflammation Robert J. Mourey, Barry Burnette, Sarah J. Brustkern, Journal of Pharmacology and Experimental Therapeutics	2010	129
Selective inhibition of the p38α MAPK–MK2 axis inhibits inflammatory cues including inflammasome priming signals Chun Wang, Susan L. Hockerman, E. Jon Jacobsen, The Journal of Experimental Medicine	2018	98
Discovery of PH-797804, a highly selective and potent inhibitor of p38 MAP kinase Shaun R. Selness, Rajesh Devraj, Balekudru Devadas, Bioorganic & Medicinal Chemistry Letters Drug TargetSignaling PathwayP38 Map KinaseBiochemistryPotent Inhibitor	2011	70
Anti-Inflammatory Properties of a Novel N-Phenyl Pyridinone Inhibitor of p38 Mitogen-Activated Protein Kinase: Preclinical-to-Clinical Translation Heidi R. Hope, Gary D. Anderson, Barry Burnette, Journal of Pharmacology and Experimental Therapeutics	2009	60
Discovery of a Potent and Selective Sphingosine Kinase 1 Inhibitor through the Molecular Combination of Chemotype-Distinct Screening Hits Mark E. Schnute, Matthew D. McReynolds, Jeffrey Carroll, Journal of Medicinal Chemistry	2017	52
High-Throughput Kinetic Characterization of Irreversible Covalent Inhibitors of KRAS<sup>G12C</sup> by Intact Protein MS and Targeted MRM Ke Sherry Li, John G. Quinn, Matthew J. Saabye, Analytical Chemistry	2022	37
Examination of the kinetic mechanism of mitogen-activated protein kinase activated protein kinase-2 John F. Schindler, Andrew Godbey, William F. Hood, Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics Signal TransductionCell RegulationBiochemistrySignaling PathwayMedicine	2002	21
Expression, purification, characterization and crystallization of non- and phosphorylated states of JAK2 and JAK3 kinase domain Troii Hall, Thomas L. Emmons, Jill Chrencik, Protein Expression and Purification Phosphorylated StatesProtein FunctionSignal TransductionJak3 Kinase DomainBiochemistry	2009	20

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