Antoine Guyon

CRISPR-Induced Deletion with SaCas9 Restores Dystrophin Expression in Dystrophic Models In Vitro and In Vivo

Benjamin Duchêne, Khadija Cherif, Jean-Paul Iyombe-Engembe et al. · Molecular Therapy · 2018 · 80 citations · Full text

Life Sciences, Genetics, Molecular Genetics +15

Base editing strategy for insertion of the A673T mutation in the APP gene to prevent the development of AD in vitro

Antoine Guyon, Joël Rousseau, Francis-Gabriel Bégin et al. · Molecular Therapy — Nucleic Acids · 2021 · 45 citations · Full text

Life Sciences, Genetics, Molecular Biology +17

The protective mutation A673T in amyloid precursor protein gene decreases Aβ peptides production for 14 forms of Familial Alzheimer’s Disease in SH-SY5Y cells

Antoine Guyon, Joël Rousseau, Gabriel Lamothe et al. · PLoS ONE · 2020 · 19 citations · Full text

Life Sciences, Genetics, Neuroscience +17

Specific mutations in genes responsible for Alzheimer and for Duchenne Muscular Dystrophy introduced by Base editing and PRIME editing

Joël Rousseau, Cédric Happi Mbakam, Antoine Guyon et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2020 · 11 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17