Jean-Paul Iyombe-Engembe

Efficient Restoration of the Dystrophin Gene Reading Frame and Protein Structure in DMD Myoblasts Using the CinDel Method

Jean-Paul Iyombe-Engembe, Dominique L. Ouellet, Xavier Barbeau et al. · Molecular Therapy — Nucleic Acids · 2016 · 79 citations · Full text

Engineering, Molecular Biology, Cytoskeleton +18

CRISPR-Induced Deletion with SaCas9 Restores Dystrophin Expression in Dystrophic Models In Vitro and In Vivo

Benjamin Duchêne, Khadija Cherif, Jean-Paul Iyombe-Engembe et al. · Molecular Therapy · 2018 · 77 citations · Full text

Crispr-induced Deletion, Engineering, Genetics +19

From gRNA Identification to the Restoration of Dystrophin Expression: A Dystrophin Gene Correction Strategy for Duchenne Muscular Dystrophy Mutations Using the CRISPR-Induced Deletion Method

Benjamin Duchêne, Jean-Paul Iyombe-Engembe, Joël Rousseau et al. · Methods in molecular biology · 2017 · 11 citations

Grna Identification, Genetics, Dystrophin Expression +10