Donna L. George

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

Jamil Momand, Gerard P. Zambetti, David C. Olson et al. · Cell · 1992 · 3.1K citations

Oncogenic Agent, Medicine, Molecular Biology +9

Amplification of a gene encoding a p53-associated protein in human sarcomas

Jonathan D. Oliner, Kenneth W. Kinzler, Paul S. Meltzer et al. · Nature · 1992 · 2K citations · Full text

Tumor Biology, Human Sarcomas, P53-associated Protein +7

The codon 72 polymorphic variants of p53 have markedly different apoptotic potential

Patrick Dumont, Julia I-Ju Leu, Anthony C. Della Pietra et al. · Nature Genetics · 2003 · 1.3K citations

Allelic Variant, Polymorphic Variants, Somatic Variant +7

Mitochondrial p53 activates Bak and causes disruption of a Bak–Mcl1 complex

Julia I-Ju Leu, Patrick Dumont, Michael J. Hafey et al. · Nature Cell Biology · 2004 · 760 citations

Mitochondrial Function, Bak–mcl1 Complex, Mitochondrial Dynamic +8

Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line.

S. Fakharzadeh, Stephen P. Trusko, Donna L. George · The EMBO Journal · 1991 · 707 citations · Full text

Tumor Biology, Medicine, Cancer Cell Biology +9