Flavonoid 4,4′-dimethoxychalcone induced ferroptosis in cancer cells by synergistically activating Keap1/Nrf2/HMOX1 pathway and inhibiting FECH

Changmei Yang, Tianxiang Wang, Yujiao Zhao, +5

Free Radical Biology and Medicine

Chemoprevention StrategyLipid PeroxidationInduced FerroptosisSecondary MetabolitesChemical Biology +19

An autoimmune disease variant of IgG1 modulates B cell activation and differentiation

Xiangjun Chen, Xiaolin Sun, W. Yang, +25

Science

Comprehensive maturity of nuclear pore complexes regulates zygotic genome activation

Weimin Shen, Bo Gong, Cencan Xing, +11

Cell

Nicotinamide Mononucleotide Alleviates LPS-Induced Inflammation and Oxidative Stress via Decreasing COX-2 Expression in Macrophages

Jing Liu, Zhaoyun Zong, Wenhao Zhang, +6

Frontiers in Molecular Biosciences

RNase-Resistant Virus-Like Particles Containing Long Chimeric RNA Sequences Produced by Two-Plasmid Coexpression System

Yuxiang Wei, Changmei Yang, Baojun Wei, +5

Journal of Clinical Microbiology

Viral ReplicationRna Virus DetectionImmunologyMolecular BiologyViral Structural Protein +14

Nicotinamide mononucleotide inhibits hepatic stellate cell activation to prevent liver fibrosis via promoting PGE2 degradation

Zhaoyun Zong, Jing Liu, Ning Wang, +6

Free Radical Biology and Medicine

Decreased NAD Activates STAT3 and Integrin Pathways to Drive Epithelial-Mesenchymal Transition

Weixuan Wang, Yadong Hu, Changmei Yang, +4

Molecular & Cellular Proteomics

Flavonoid 4,4′-dimethoxychalcone selectively eliminates senescent cells via activating ferritinophagy

Tianxiang Wang, Changmei Yang, Zhiqiang Li, +8

Redox Biology

Nicotinamide Mononucleotide Administration Restores Redox Homeostasis via the Sirt3–Nrf2 Axis and Protects Aged Mice from Oxidative Stress-Induced Liver Injury

Chengting Luo, Wenxi Ding, Changmei Yang, +3

Journal of Proteome Research

AgingRedox HomeostasisBiogerontologyRedox BiologyOxidative Stress +16

Flavonoid 4,4′-dimethoxychalcone suppresses cell proliferation via dehydrogenase inhibition and oxidative stress aggravation

Changmei Yang, Songbiao Zhu, Yuling Chen, +5

Free Radical Biology and Medicine