The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery

Yun Xia, Yonghua Xie, Zhengsen Yu, +20

Cell

VaccinationDruggable TargetVaccine DevelopmentVaccine ResearchVaccine Target +9

M1 Macrophages Induce PD-L1 Expression in Hepatocellular Carcinoma Cells Through IL-1β Signaling

Zhaoyun Zong, Jiahuan Zou, Rudi Mao, +7

Frontiers in Immunology

Cross-talk between TNF-α and IFN-γ signaling in induction of B7-H1 expression in hepatocellular carcinoma cells

Na Li, Jianing Wang, Na Zhang, +8

Cancer Immunology Immunotherapy

Tumor BiologyHepatologyMedicineLiver PhysiologyImmunology +10

Nicotinamide Mononucleotide Alleviates LPS-Induced Inflammation and Oxidative Stress via Decreasing COX-2 Expression in Macrophages

Jing Liu, Zhaoyun Zong, Wenhao Zhang, +6

Frontiers in Molecular Biosciences

Nicotinamide mononucleotide inhibits hepatic stellate cell activation to prevent liver fibrosis via promoting PGE2 degradation

Zhaoyun Zong, Jing Liu, Ning Wang, +6

Free Radical Biology and Medicine

Reduced Nicotinamide Mononucleotide (NMNH) Potently Enhances NAD ⁺ and Suppresses Glycolysis, the TCA Cycle, and Cell Growth

Yan Liu, Chengting Luo, Ting Li, +4

Journal of Proteome Research

ISG15 silencing increases cisplatin resistance via activating p53-mediated cell DNA repair

Yi Huo, Zhaoyun Zong, Qingtao Wang, +2

Oncotarget

Cisplatin ResistanceTumor BiologyGenome InstabilityChromatinChromatin Remodeling +10

Flavonoid 4,4′-dimethoxychalcone selectively eliminates senescent cells via activating ferritinophagy

Tianxiang Wang, Changmei Yang, Zhiqiang Li, +8

Redox Biology

A20 inhibits the motility of HCC cells induced by TNF-α

Xianteng Wang, Chao Ma, Zhaoyun Zong, +5

Oncotarget

ApoptosisImmunologyImmune RegulationPathologyImmunologic Mechanism +21

Nicotinamide <i>N</i>-Methyltransferase Remodeled Cell Metabolism and Aggravated Proinflammatory Responses by Activating STAT3/IL1β/PGE₂ Pathway

Changmei Yang, Tianxiang Wang, Songbiao Zhu, +8

ACS Omega