Widespread Enhancer Dememorization and Promoter Priming during Parental-to-Zygotic Transition

Bingjie Zhang, Xiaotong Wu, Wenhao Zhang, +8

Molecular Cell

Transcriptional RegulationDevelopmental BiologyGeneticsGenetic MechanismMolecular Genetics +7

Maternal Ybx1 safeguards zebrafish oocyte maturation and maternal-to-zygotic transition by repressing global translation

Jiawei Sun, Lu Yan, Weimin Shen, +1

Development

Maternal Huluwa dictates the embryonic body axis through β-catenin in vertebrates

Lu Yan, Jing Chen, Xuechen Zhu, +6

Science

Comprehensive maturity of nuclear pore complexes regulates zygotic genome activation

Weimin Shen, Bo Gong, Cencan Xing, +11

Cell

Treadmill exercise promotes neurogenesis and myelin repair via upregulating Wnt/β‑catenin signaling pathways in the juvenile brain following focal cerebral ischemia/reperfusion

Jing‐Yan Cheng, Weimin Shen, Lingqin Jin, +8

International Journal of Molecular Medicine

Brain DevelopmentTreadmill ExerciseCerebral Vascular RegulationNeuroregenerationNeurobiology Of Disease +21

5′ Half of specific tRNAs feeds back to promote corresponding tRNA gene transcription in vertebrate embryos

Luxi Chen, Wei Xu, Kunpeng Liu, +8

Science Advances

Mapping putative enhancers in mouse oocytes and early embryos reveals TCF3/12 as key folliculogenesis regulators

Bofeng Liu, Yuanlin He, Xiaotong Wu, +18

Nature Cell Biology

Key Folliculogenesis RegulatorsDevelopmental BiologyTissue DevelopmentOogenesisMorphogenesis +5

The Sec14-like phosphatidylinositol transfer proteins Sec14l3/SEC14L2 act as GTPase proteins to mediate Wnt/Ca2+ signaling

Bo Gong, Weimin Shen, Wanghua Xiao, +3

eLife

Treadmill exercise enhances synaptic plasticity in the ischemic penumbra of MCAO mice by inducing the expression of Camk2a via CYFIP1 upregulation

Weimin Shen, Lingqin Jin, Anqi Zhu, +9

Life Sciences

Synaptic PlasticityMolecular PhysiologySignal TransductionNeurophysiologyCell Signaling +11

Generation of iPSC-derived human venous endothelial cells for the modeling of vascular malformations and drug discovery

Zihang Pan, Qiyang Yao, Weijing Kong, +27

Cell stem cell

EngineeringBiomedical EngineeringVascular MalformationsRegenerative MedicineAngiogenesis +19