Microglial α7 nicotinic acetylcholine receptors drive a phospholipase C/IP₃pathway and modulate the cell activation toward a neuroprotective role

Tomohisa Suzuki, Izumi Hide, Akiyo Matsubara, +9

Journal of Neuroscience Research

Multitargeted Effects of Hangeshashinto for Treatment of Chemotherapy-Induced Oral Mucositis on Inducible Prostaglandin E2 Production in Human Oral Keratinocytes

Toru Kono, Atsushi Kaneko, Chinami Matsumoto, +5

Integrative Cancer Therapies

Angiotensin type 1 receptor antagonist inhibits lipopolysaccharide‐induced stimulation of rat microglial cells by suppressing nuclear factor κB and activator protein‐1 activation

Michio Miyoshi, Kanako Miyano, Naoki Moriyama, +2

European Journal of Neuroscience

Neuropeptide oxytocin enhances μ opioid receptor signaling as a positive allosteric modulator

Yoshiyuki Meguro, Kanako Miyano, Shigeto Hirayama, +13

Journal of Pharmacological Sciences

Hydroxy-α sanshool induces colonic motor activity in rat proximal colon: a possible involvement of KCNK9

Kunitsugu Kubota, Nobuhiro Ohtake, Katsuya Ohbuchi, +7

American Journal of Physiology-Gastrointestinal and Liver Physiology

Molecular PharmacologyPossible InvolvementTrpv1/trpa1 AgonistMolecular PhysiologyBiochemistry +11

Goshajinkigan, a Traditional Japanese Medicine, Prevents Oxaliplatin-Induced Acute Peripheral Neuropathy by Suppressing Functional Alteration of TRP Channels in Rat

Keita Mizuno, Toru Kono, Yasuyuki Suzuki, +5

Journal of Pharmacological Sciences

Activation of the neurokinin-1 receptor in rat spinal astrocytes induces Ca2+ release from IP3-sensitive Ca2+ stores and extracellular Ca2+ influx through TRPC3

Kanako Miyano, Norimitsu Morioka, Tatsuhiko Sugimoto, +3

Neurochemistry International

NeuroregenerationMolecular PhysiologyNeurophysiologyMedicinePhysiology +11

Development of ghrelin resistance in a cancer cachexia rat model using human gastric cancer-derived 85As2 cells and the palliative effects of the Kampo medicine rikkunshito on the model

Kiyoshi Terawaki, Yohei Kashiwase, Yumi Sawada, +13

PLoS ONE

Chemoprevention StrategyGastroenterologyPathologyFood IntakeCaloric Restriction +16

Activation of transient receptor potential ankyrin 1 evokes nociception through substance P release from primary sensory neurons

Yoki Nakamura, Yujiro Une, Kanako Miyano, +4

Journal of Neurochemistry

Evokes NociceptionAnesthetic MechanismNeuropathic PainMolecular PainSubstance P +15

New cancer cachexia rat model generated by implantation of a peritoneal dissemination-derived human stomach cancer cell line

Kiyoshi Terawaki, Yumi Sawada, Yohei Kashiwase, +11

American Journal of Physiology-Endocrinology and Metabolism

OncologyCancer CachexiaChemoprevention StrategyMedicinePharmacology +13