Alexander F. A. Keszei

STING cyclic dinucleotide sensing originated in bacteria

Benjamin R. Morehouse, Apurva A. Govande, Adi Millman et al. · Nature · 2020 · 372 citations · Full text

Oligonucleotide, Molecular Biology, Microbiology +2

Cyclic CMP and cyclic UMP mediate bacterial immunity against phages

Nitzan Tal, Benjamin R. Morehouse, Adi Millman et al. · Cell · 2021 · 268 citations · Full text

Biology, Medicine, Cyclic Cmp +7

CBASS Immunity Uses CARF-Related Effectors to Sense 3′–5′- and 2′–5′-Linked Cyclic Oligonucleotide Signals and Protect Bacteria from Phage Infection

B. Lowey, Aaron T. Whiteley, Alexander F. A. Keszei et al. · Cell · 2020 · 242 citations · Full text

Immune Effector Functions, Protect Bacteria, Medicine +14

Cryo-EM structure of an active bacterial TIR–STING filament complex

Benjamin R. Morehouse, Matthew C. J. Yip, Alexander F. A. Keszei et al. · Nature · 2022 · 114 citations · Full text

Structure of an SspH1-PKN1 Complex Reveals the Basis for Host Substrate Recognition and Mechanism of Activation for a Bacterial E3 Ubiquitin Ligase

Alexander F. A. Keszei, Xiaojing Tang, Craig McCormick et al. · Molecular and Cellular Biology · 2013 · 98 citations · Full text

Host Substrate Recognition, Protein Function, Protein Assembly +14