B. Lowey

STING cyclic dinucleotide sensing originated in bacteria

Benjamin R. Morehouse, Apurva A. Govande, Adi Millman et al. · Nature · 2020 · 372 citations · Full text

Oligonucleotide, Molecular Biology, Microbiology +2

Bacterial cGAS-like enzymes synthesize diverse nucleotide signals

Aaron T. Whiteley, James B. Eaglesham, Carina C. de Oliveira Mann et al. · Nature · 2019 · 371 citations · Full text

Biosynthesis, Engineering, Synthetic Biology +4

Bacterial gasdermins reveal an ancient mechanism of cell death

Alex G. Johnson, Tanita Wein, Megan L. Mayer et al. · Science · 2022 · 246 citations · Full text

CBASS Immunity Uses CARF-Related Effectors to Sense 3′–5′- and 2′–5′-Linked Cyclic Oligonucleotide Signals and Protect Bacteria from Phage Infection

B. Lowey, Aaron T. Whiteley, Alexander F. A. Keszei et al. · Cell · 2020 · 242 citations · Full text

Immune Effector Functions, Protect Bacteria, Medicine +14

Structure and Mechanism of a Cyclic Trinucleotide-Activated Bacterial Endonuclease Mediating Bacteriophage Immunity

Rebecca Lau, Qiaozhen Ye, Erica A. Birkholz et al. · Molecular Cell · 2020 · 203 citations · Full text

Natural Sciences, Virulence Factor, Pathogenesis +7