Klara R. Klein

Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras

Haiyan Yu, Nicholas W. Hughes, Bingxu Liu et al. · Cell · 2017 · 664 citations · Full text

Functional Genomics, Oncogenic Ras, Synthetic Lethal Interactions +10

Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial

W. Timothy Garvey, Juan P. Frías, Ania M. Jastreboff et al. · The Lancet · 2023 · 590 citations · Full text

Obesity, Metabolic Syndrome, Diabetes Management +6

Once-Weekly Semaglutide in Adults With Alcohol Use Disorder

Christian S. Hendershot, Michael P. Bremmer, Michael B. Paladino et al. · JAMA Psychiatry · 2025 · 119 citations · Full text

Decoy Receptor CXCR7 Modulates Adrenomedullin-Mediated Cardiac and Lymphatic Vascular Development

Klara R. Klein, Natalie O. Karpinich, Scott T. Espenschied et al. · Developmental Cell · 2014 · 101 citations · Full text

Inflammation, Cardiac Muscle, Signal Transduction +7

Validation of distinct type 2 diabetes clusters and their association with diabetes complications in the <scp>DEVOTE</scp> , <scp>LEADER</scp> and <scp>SUSTAIN</scp> ‐6 cardiovascular outcomes trials

Anna R. Kahkoska, Milan S. Geybels, Klara R. Klein et al. · Diabetes Obesity and Metabolism · 2020 · 73 citations · Full text