Lipocalin 2 is essential for chronic kidney disease progression in mice and humans

Amandine Viau, Khalil El Karoui, Denise Laouari, +10

Journal of Clinical Investigation

AKT2 is essential to maintain podocyte viability and function during chronic kidney disease

Guillaume Canaud, Frank Bienaimé, Amandine Viau, +14

Nature Medicine

InflammationUrologyRenal DiseaseRenal FunctionMedicine +11

Primary-cilium-dependent autophagy controls epithelial cell volume in response to fluid flow

Idil Orhon, Nicolas Dupont, Mohamad Zaidan, +10

Nature Cell Biology

Cell AutophagyMitophagyEpendymaEpithelial Cell VolumePhysiology +9

Endoplasmic reticulum stress drives proteinuria-induced kidney lesions via Lipocalin 2

Khalil El Karoui, Amandine Viau, Olivier Dellis, +14

Nature Communications

Cilia‐localized <scp>LKB</scp> 1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney

Amandine Viau, Frank Bienaimé, Kamile Lukas, +24

The EMBO Journal

Stat3 Controls Tubulointerstitial Communication during CKD

Frank Bienaimé, Mordi Muorah, Lucie Yammine, +14

Journal of the American Society of Nephrology

ImmunologyRenal InflammationCellular PhysiologyInflammationRenal Function +15

Targeting mTOR Signaling Can Prevent the Progression of FSGS

Stefan Zschiedrich, Tillmann Bork, Wei Liang, +19

Journal of the American Society of Nephrology

Agonists of prostaglandin E ₂ receptors as potential first in class treatment for nephronophthisis and related ciliopathies

Hugo García, Alice Serafin, Flora Silbermann, +26

Proceedings of the National Academy of Sciences

Renal PathologyRenal InflammationProstaglandin E1Nph ZebrafishNphp1 Knockdown Cells +21

Loss of PKD1/polycystin-1 impairs lysosomal activity in a CAPN (calpain)-dependent manner

Lukas Peintner, Anusha Venkatraman, Astrid Waeldin, +7

Autophagy

A large tandem duplication within the COL4A5 gene is responsible for the high prevalence of Alport syndrome in French Polynesia

Christelle Arrondel, Georges Deschênes, Yannick Le Meur, +7

Kidney International

BiologyMendelian DisorderGenetic DisorderFrench PolynesiaGenetics +8