Daisuke Tomimoto

JTT-130, a Novel Intestine-Specific Inhibitor of Microsomal Triglyceride Transfer Protein, Suppresses Food Intake and Gastric Emptying with the Elevation of Plasma Peptide YY and Glucagon-Like Peptide-1 in a Dietary Fat-Dependent Manner

Takahiro Hata, Yasuko Mera, Yukihito Ishii et al. · Journal of Pharmacology and Experimental Therapeutics · 2010 · 41 citations

Life Sciences, Endocrinology, Pharmacology +15

Discovery of 6-Phenylpyrimido[4,5-<i>b</i>][1,4]oxazines as Potent and Selective Acyl CoA:Diacylglycerol Acyltransferase 1 (DGAT1) Inhibitors with in Vivo Efficacy in Rodents

Brian M. Fox, Kazuyuki Sugimoto, Kiyosei Iio et al. · Journal of Medicinal Chemistry · 2014 · 30 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

A pyruvate dehydrogenase kinase inhibitor prevents retinal cell death and improves energy metabolism in rat retinas after ischemia/reperfusion injury

Kota Sato, Seiya Mochida, Daisuke Tomimoto et al. · Experimental Eye Research · 2020 · 29 citations · Full text

Medicine, Ophthalmology, Pharmacology +17

A Novel TNF-α Converting Enzyme (TACE) Selective Inhibitor JTP-96193 Prevents Insulin Resistance in KK-A&lt;sup&gt;y&lt;/sup&gt; Type 2 Diabetic Mice and Diabetic Peripheral Neuropathy in Type 1 Diabetic Mice

Mariko Maekawa, Hironobu Tadaki, Daisuke Tomimoto et al. · Biological and Pharmaceutical Bulletin · 2019 · 22 citations · Full text

Medicine, Molecular Biology, Pharmacology +15

JTT-553, a novel Acyl CoA:diacylglycerol acyltransferase (DGAT) 1 inhibitor, improves glucose metabolism in diet-induced obesity and genetic T2DM mice

Daisuke Tomimoto, Chihiro Okuma, Yukihito Ishii et al. · Journal of Pharmacological Sciences · 2015 · 20 citations · Full text

Medicine, Endocrinology, Pharmacology +17