Shogo Misumi

A small molecule compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replication

Shin-ichiro Hattori, Nobuyo Higashi‐Kuwata, Hironori Hayashi et al. · Nature Communications · 2021 · 190 citations · Full text

GRL-0920, an Indole Chloropyridinyl Ester, Completely Blocks SARS-CoV-2 Infection

Shin-ichiro Hattori, Nobuyo Higshi-Kuwata, Jakka Raghavaiah et al. · mBio · 2020 · 78 citations · Full text

Dimerization of HIV-1 protease occurs through two steps relating to the mechanism of protease dimerization inhibition by darunavir

Hironori Hayashi, Nobutoki Takamune, Takashi Nirasawa et al. · Proceedings of the National Academy of Sciences · 2014 · 77 citations · Full text

Irreversible Inhibition of Metallo‐β‐lactamase (IMP‐1) by 3‐(3‐Mercaptopropionylsulfanyl)propionic Acid Pentafluorophenyl Ester

Hiromasa Kurosaki, Yoshihiro Yamaguchi, Toshihiro Higashi et al. · Angewandte Chemie International Edition · 2005 · 71 citations

Covalent Amide Bond, Molecular Biology, Antibiotic Resistance +21

Design and evaluation of polypseudorotaxanes of pegylated insulin with cyclodextrins as sustained release system

Taishi Higashi, Fumitoshi Hirayama, Shogo Misumi et al. · Biomaterials · 2008 · 70 citations

Pegylated Insulin, Polymer-drug Conjugate, Cyclodextrin Production +6