Nobutoki Takamune

A small molecule compound with an indole moiety inhibits the main protease of SARS-CoV-2 and blocks virus replication

Shin-ichiro Hattori, Nobuyo Higashi‐Kuwata, Hironori Hayashi et al. · Nature Communications · 2021 · 190 citations · Full text

GRL-0920, an Indole Chloropyridinyl Ester, Completely Blocks SARS-CoV-2 Infection

Shin-ichiro Hattori, Nobuyo Higshi-Kuwata, Jakka Raghavaiah et al. · mBio · 2020 · 78 citations · Full text

Dimerization of HIV-1 protease occurs through two steps relating to the mechanism of protease dimerization inhibition by darunavir

Hironori Hayashi, Nobutoki Takamune, Takashi Nirasawa et al. · Proceedings of the National Academy of Sciences · 2014 · 77 citations · Full text

Central Nervous System Compartmentalization of HIV-1 Subtype C Variants Early and Late in Infection in Young Children

Christa Buckheit Sturdevant, Anna Dow, Cassandra B. Jabara et al. · PLoS Pathogens · 2012 · 73 citations · Full text

Primary Immunodeficiency, Neurovirology, Subtype C Hiv-1 +14

Uncoating of Human Immunodeficiency Virus Type 1 Requires Prolyl Isomerase Pin1

Shogo Misumi, M. Inoue, Takeo Dochi et al. · Journal of Biological Chemistry · 2010 · 63 citations · Full text