An enhanced CRISPR repressor for targeted mammalian gene regulation

Nan Cher Yeo, Alejandro Chavez, Alissa Lance‐Byrne, +17

Nature Methods

Transcriptional RegulationNatural SciencesMolecular BiologyGene EditingGenome Editing +4

High-throughput creation and functional profiling of DNA sequence variant libraries using CRISPR–Cas9 in yeast

Xiaoge Guo, Alejandro Chavez, Angela Tung, +10

Nature Biotechnology

Functional GenomicsEngineeringGeneticsSynthetic BiologyGenetic Engineering +9

Accurate analysis of genuine CRISPR editing events with ampliCan

Kornel Labun, Xiaoge Guo, Alejandro Chavez, +3

Genome Research

EngineeringGeneticsMolecular BiologyGenomicsGenome Editing Experiment +14

Inactivation of the Sas2 histone acetyltransferase delays senescence driven by telomere dysfunction

Marina Kozak, Alejandro Chavez, Weiwei Dang, +4

The EMBO Journal

ChromatinGenome InstabilityDevelopmental BiologyChromatin StructureChromatin Remodeling +9

Regulation of hetDNA Length during Mitotic Double-Strand Break Repair in Yeast

Xiaoge Guo, Yee Fang Hum, Kevin Lehner, +1

Molecular Cell

Hetdna LengthChromatinGenome InstabilityDna DamageCell Division +9

Abnormalities of Regional Brain Activity in Patients With Schizophrenia: A Longitudinal Resting-State fMRI Study

Xue Li, Qing Liu, Zhaonian Chen, +17

Schizophrenia Bulletin

SMRT Sequencing for Parallel Analysis of Multiple Targets and Accurate SNP Phasing

Xiaoge Guo, Kevin Lehner, Karen O’Connell, +3

G3 Genes Genomes Genetics

Single-molecule Real-timeLinkage IdentificationEngineeringGeneticsPathology +19

Orgo-Seq integrates single-cell and bulk transcriptomic data to identify cell type specific-driver genes associated with autism spectrum disorder

Elaine T. Lim, Yingleong Chan, Pepper Dawes, +17

Nature Communications

An integrated pipeline for mammalian genetic screening

Christian Kramme, Alexandru M. Pleşa, Helen H. Wang, +6

Cell Reports Methods

Genetic TestingEngineeringBiomolecular ToolGeneticsMolecular Biology +15

CRISPR Guide RNA Cloning for Mammalian Systems

Sathiji Nageshwaran, Alejandro Chavez, Nan Cher Yeo, +5

Journal of Visualized Experiments

EngineeringGenome SurgeryGuide RnaGeneticsMammalian Systems +12