Xiaoge Guo

An enhanced CRISPR repressor for targeted mammalian gene regulation

Nan Cher Yeo, Alejandro Chavez, Alissa Lance‐Byrne et al. · Nature Methods · 2018 · 518 citations · Full text

Transcriptional Regulation, Natural Sciences, Molecular Biology +6

High-throughput creation and functional profiling of DNA sequence variant libraries using CRISPR–Cas9 in yeast

Xiaoge Guo, Alejandro Chavez, Angela Tung et al. · Nature Biotechnology · 2018 · 105 citations · Full text

Functional Genomics, Engineering, Genetics +11

Accurate analysis of genuine CRISPR editing events with ampliCan

Kornel Labun, Xiaoge Guo, Alejandro Chavez et al. · Genome Research · 2019 · 91 citations · Full text

Engineering, Genetics, Molecular Biology +16

Inactivation of the Sas2 histone acetyltransferase delays senescence driven by telomere dysfunction

Marina Kozak, Alejandro Chavez, Weiwei Dang et al. · The EMBO Journal · 2009 · 54 citations · Full text

Chromatin, Genome Instability, Developmental Biology +11

Regulation of hetDNA Length during Mitotic Double-Strand Break Repair in Yeast

Xiaoge Guo, Yee Fang Hum, Kevin Lehner et al. · Molecular Cell · 2017 · 47 citations · Full text

Hetdna Length, Chromatin, Genome Instability +11