MUC1 and HIF-1alpha Signaling Crosstalk Induces Anabolic Glucose Metabolism to Impart Gemcitabine Resistance to Pancreatic Cancer

Surendra K. Shukla, Vinee Purohit, Kamiya Mehla, +34

Cancer Cell

Tumor BiologyImpart Gemcitabine ResistancePancreatic CancerOncogenic AgentMedicine +5

Metabolic Rewiring by Loss of Sirt5 Promotes Kras-Induced Pancreatic Cancer Progression

Tuo Hu, Surendra K. Shukla, Enza Vernucci, +28

Gastroenterology

GOT1-mediated anaplerotic glutamine metabolism regulates chronic acidosis stress in pancreatic cancer cells

Jaime Abrego, Venugopal Gunda, Enza Vernucci, +7

Cancer Letters

Reductive StressPancreatic CancerMedicineCatabolismChronic Acidosis Stress +8

SIRT1–NOX4 signaling axis regulates cancer cachexia

Aneesha Dasgupta, Surendra K. Shukla, Enza Vernucci, +27

The Journal of Experimental Medicine

Tumor BiologyRadiation OncologySirt1 ExpressionChemoprevention StrategySkeletal Muscle +11

Classical autophagy proteins LC3B and ATG4B facilitate melanosome movement on cytoskeletal tracks

Amrita Ramkumar, Divya Murthy, Desingu Ayyappa Raja, +10

Autophagy

MitophagyMolecular BiologyCytoskeletonCellular PhysiologyCell Autophagy +14

Cancer-associated fibroblast-derived acetate promotes pancreatic cancer development by altering polyamine metabolism via the ACSS2–SP1–SAT1 axis

Divya Murthy, Kuldeep S. Attri, Surendra K. Shukla, +34

Nature Cell Biology

Vitamin B6 Competition in the Tumor Microenvironment Hampers Antitumor Functions of NK Cells

Chunbo He, Dezhen Wang, Surendra K. Shukla, +15

Cancer Discovery

JNK signaling contributes to skeletal muscle wasting and protein turnover in pancreatic cancer cachexia

Scott E. Mulder, Aneesha Dasgupta, Ryan J. King, +5

Cancer Letters

Signal TransductionSignaling PathwaySkeletal Muscle WastingPancreatic Cancer CachexiaCell Signaling +9

The Molecular Mechanism Underlying Recruitment and Insertion of Lipid-Anchored LC3 Protein into Membranes

Lipi Thukral, Durba Sengupta, Amrita Ramkumar, +3

Biophysical Journal

Proteinlipid InteractionSignal TransductionBiochemistryNatural SciencesMolecular Biology +6

Standardization of the oral glucose tolerance test and the criteria for diagnosis of chemical diabetes in children

Richard A. Guthrie, Diana Guthrie, Divya Murthy, +2

Metabolism

Diabetes ManagementDiabetesPediatricsBlood Glucose MonitoringPediatric Endocrinology +3