Mami Shibata‐Koyama

Structural basis for improved efficacy of therapeutic antibodies on defucosylation of their Fc glycans

Tsunehiro Mizushima, Hirokazu Yagi, Emi Takemoto et al. · Genes to Cells · 2011 · 239 citations · Full text

Crystal Structure, Glycobiology, Immunology +22

A Nonfucosylated Variant of the anti-HIV-1 Monoclonal Antibody b12 Has Enhanced FcγRIIIa-Mediated Antiviral Activity <i>In Vitro</i> but Does Not Improve Protection against Mucosal SHIV Challenge in Macaques

Brian Moldt, Mami Shibata‐Koyama, Eva G. Rakasz et al. · Journal of Virology · 2012 · 116 citations · Full text

Nonfucosylated rituximab potentiates human neutrophil phagocytosis through its high binding for FcγRIIIb and MHC class II expression on the phagocytotic neutrophils

Mami Shibata‐Koyama, Shigeru Iida, Hirofumi Misaka et al. · Experimental Hematology · 2009 · 114 citations

Inflammation, Immune Effector Functions, Microbial Pathogens +14

The N-linked oligosaccharide at Fc RIIIa Asn-45: an inhibitory element for high Fc RIIIa binding affinity to IgG glycoforms lacking core fucosylation

Mami Shibata‐Koyama, S. Iida, Akira Okazaki et al. · Glycobiology · 2008 · 112 citations · Full text

Importance of the Side Chain at Position 296 of Antibody Fc in Interactions with FcγRIIIa and Other Fcγ Receptors

Yuya Isoda, Hirokazu Yagi, Tadashi Satoh et al. · PLoS ONE · 2015 · 26 citations · Full text