Paul T. Schumacker

Reactive Oxygen Species Generated at Mitochondrial Complex III Stabilize Hypoxia-inducible Factor-1α during Hypoxia

Navdeep S. Chandel, David S. McClintock, Carlos E. Feliciano et al. · Journal of Biological Chemistry · 2000 · 1.9K citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Mitochondrial reactive oxygen species trigger hypoxia-induced transcription

Navdeep S. Chandel, Emin Maltepe, Eugene Goldwasser et al. · Proceedings of the National Academy of Sciences · 1998 · 1.9K citations · Full text

Life Sciences, Cell Biology, Physiology +17

Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing

Robert D. Guzy, Beatrice Hoyos, Emmanuel Robin et al. · Cell Metabolism · 2005 · 1.5K citations · Full text

Life Sciences, Biochemistry, Cell Biology +16

Bcl-xL Regulates the Membrane Potential and Volume Homeostasis of Mitochondria

Matthew G. Vander Heiden, Navdeep S. Chandel, Edward K. Williamson et al. · Cell · 1997 · 1.4K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Mitochondria Are Required for Antigen-Specific T Cell Activation through Reactive Oxygen Species Signaling

Laura A. Sena, Sha Li, Amit Jairaman et al. · Immunity · 2013 · 1.3K citations · Full text

Life Sciences, Cell Biology, Immunology +14