Sari Pappinen

Interaction of lipid nanoparticles with human epidermis and an organotypic cell culture model

Judith Kuntsche, Heike Bunjes, Alfred Fahr et al. · International Journal of Pharmaceutics · 2007 · 96 citations

Nanoparticles, Lipid Preparation, Engineering +6

IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 2: An introduction to the simulation exercise and overview of results

Alison Margolskee, Adam S. Darwich, Xavier Pépin et al. · European Journal of Pharmaceutical Sciences · 2016 · 66 citations · Full text

Pharmacokinetic Modeling, Medicine, Process Analytical Technology +6

IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across different compound classes

Adam S. Darwich, Alison Margolskee, Xavier Pépin et al. · European Journal of Pharmaceutical Sciences · 2016 · 45 citations · Full text

Systems Pharmacology, Silico Performance, Pharmacokinetic Modeling +13

Comparison of rat epidermal keratinocyte organotypic culture (ROC) with intact human skin: Lipid composition and thermal phase behavior of the stratum corneum

Sari Pappinen, Martin Hermansson, Judith Kuntsche et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 2008 · 42 citations

Ophthalmology, Stratum Corneum, Intact Human Skin +8

IMI – Oral biopharmaceutics tools project – Evaluation of bottom-up PBPK prediction success part 4: Prediction accuracy and software comparisons with improved data and modelling strategies

Xavier Pépin, Leon Aarons, Yuya Wang et al. · European Journal of Pharmaceutics and Biopharmaceutics · 2020 · 36 citations · Full text

Pharmacokinetic Modeling, Prediction Accuracy, Modelling Strategies +9