A Pattern-Based Method for the Identification of MicroRNA Binding Sites and Their Corresponding Heteroduplexes

Kevin C. Miranda, Yvonne Tay, Yen-Sin Ang, +4

Cell

Systems BiologyFunctional GenomicsTheir Corresponding HeteroduplexesNatural SciencesGenetics +12

Slug and Sox9 Cooperatively Determine the Mammary Stem Cell State

Wenjun Guo, Zuzana Keckesova, Joana Liu Donaher, +11

Cell

Embryonic Stem CellCell LineageDevelopmental BiologyCell DivisionMedicine +8

XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway

Xi Chen, Dimitrios Iliopoulos, Qing Zhang, +21

Nature

Distinct EMT programs control normal mammary stem cells and tumour-initiating cells

Xin Ye, Wai Leong Tam, Tsukasa Shibue, +4

Nature

Induced Pluripotent Stem CellDevelopmental BiologyMedicineAdult Stem CellTumour-initiating Cells +7

Reciprocal Transcriptional Regulation of <i>Pou5f1</i> and <i>Sox2</i> via the Oct4/Sox2 Complex in Embryonic Stem Cells

Joon-Lin Chew, Yuin‐Han Loh, Wensheng Zhang, +8

Molecular and Cellular Biology

GeneticsStem Cell BiologyCell SpecializationHuman EscsTranscriptional Regulation +17

Sall4 modulates embryonic stem cell pluripotency and early embryonic development by the transcriptional regulation of Pou5f1

Jinqiu Zhang, Wai Leong Tam, Guo Qing Tong, +11

Nature Cell Biology

Transcriptional RegulationInduced Pluripotent Stem CellDevelopmental BiologyEarly Embryonic DevelopmentMedicine +6

Genomic landscape of lung adenocarcinoma in East Asians

Jianbin Chen, Hechuan Yang, Audrey Su Min Teo, +40

Nature Genetics

PathologyCancer GenomicsBronchial NeoplasmEast AsiansMedicine +1

A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages

Haihui Lu, Karl R. Clauser, Wai Leong Tam, +8

Nature Cell Biology

Lineage PlasticityBreast OncologyBreast Cancer StemMedicineAdult Stem Cell +8

Methionine is a metabolic dependency of tumor-initiating cells

Zhenxun Wang, Lian Yee Yip, Jia Hui Jane Lee, +21

Nature Medicine

MedicineMetabolic RemodelingMetabolic DependencyCancer BiologyRadiation Oncology +3

Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability

Diwakar R. Pattabiraman, Brian Bierie, Katharina I Kober, +6

Science

Cancer ResearchEpithelial-mesenchymal TransitionProtein Kinase ADevelopmental BiologyPerineural Invasion +13