NADP+-IDH Mutations Promote Hypersuccinylation that Impairs Mitochondria Respiration and Induces Apoptosis Resistance

Li Feng, Xiadi He, Dingwei Ye, +18

Molecular Cell

Reductive StressImpairs Mitochondria RespirationInduces Apoptosis ResistanceMitochondrial FunctionBiochemistry +6

Sensing and Transmitting Intracellular Amino Acid Signals through Reversible Lysine Aminoacylations

Xiadi He, Wei Gong, Jianong Zhang, +20

Cell Metabolism

Signal TransductionBiochemistryNatural SciencesPeptide LibraryMolecular Biology +4

SPOP mutation induces DNA methylation via stabilizing GLP/G9a

Jianong Zhang, Kun Gao, Hongyan Xie, +19

Nature Communications

A lncRNA from the FTO locus acts as a suppressor of the m6A writer complex and p53 tumor suppression signaling

Jianong Zhang, Jiangbo Wei, Rui Sun, +16

Molecular Cell

Mitochondrial STAT5A promotes metabolic remodeling and the Warburg effect by inactivating the pyruvate dehydrogenase complex

Liang Zhang, Jianong Zhang, Yan Liu, +14

Cell Death and Disease

SETDB1 Modulates Degradation of Phosphorylated RB and Anticancer Efficacy of CDK4/6 Inhibitors

Zhenlin Huang, Xiang Li, Bo Tang, +15

Cancer Research

CYCLIN K down-regulation induces androgen receptor gene intronic polyadenylation, variant expression and PARP inhibitor vulnerability in castration-resistant prostate cancer

Rui Sun, Ting Wei, Donglin Ding, +5

Proceedings of the National Academy of Sciences

iASPP–PP1 complex is required for cytokinetic abscission by controlling CEP55 dephosphorylation

Kun Gao, Yuanyuan Zhang, Qing Shi, +13

Cell Death and Disease

Gain-of-function mutant p53 together with ERG proto-oncogene drive prostate cancer by beta-catenin activation and pyrimidine synthesis

Donglin Ding, Alexandra M. Blee, Jianong Zhang, +6

Nature Communications

PTEN loss promotes Warburg effect and prostate cancer cell growth by inducing FBP1 degradation

Changze Song, Jianong Zhang, Xiao Liu, +9

Frontiers in Oncology