M S Chen

Effect of incorporation of cidofovir into DNA by human cytomegalovirus DNA polymerase on DNA elongation

Xiaofeng Xiong, Jeffrey L. Smith, M S Chen · Antimicrobial Agents and Chemotherapy · 1997 · 183 citations · Full text

Viral Replication, Molecular Virology, Biochemistry +15

Novel mutation (K70E) in human immunodeficiency virus type 1 reverse transcriptase confers decreased susceptibility to 9-[2-(phosphonomethoxy)ethyl]adenine in vitro

Julie M. Cherrington, Andrew Mulato, Michael D. Fuller et al. · Antimicrobial Agents and Chemotherapy · 1996 · 61 citations · Full text

Novel Mutation, Biochemistry, Natural Sciences +14

Biochemical basis for increased susceptibility to Cidofovir of herpes simplex viruses with altered or deficient thymidine kinase activity

Dirk B. Mendel, D B Barkhimer, M S Chen · Antimicrobial Agents and Chemotherapy · 1995 · 51 citations · Full text

Viral Replication, Molecular Virology, Pathogenesis +12

Conversion of 1-[((S)-2-hydroxy-2-oxo-1,4,2-dioxaphosphorinan-5-yl)methyl]cytosine to cidofovir by an intracellular cyclic CMP phosphodiesterase

Dirk B. Mendel, Tomáš Cihlář, Keith Moon et al. · Antimicrobial Agents and Chemotherapy · 1997 · 44 citations · Full text

Antiviral Compound, Human Enzyme, Biochemistry +10

Comparative kinetic analyses of interaction of inhibitors with Rauscher murine leukemia virus and human immunodeficiency virus reverse transcriptases

Julie M. Cherrington, Michael D. Fuller, Andrew Mulato et al. · Antimicrobial Agents and Chemotherapy · 1996 · 20 citations · Full text

Immunology, Antiviral Drug, Human Immunodeficiency Virus +16